Dive into the ultimate comfort food with my Meat Lovers Pizza Casserole! This hearty meal combines ground beef, Italian sausage, and more, all layered with gooey cheese. It's simple to make and a surefire hit for family dinners or game days. Ready to learn how to craft this satisfying dish? Let’s gather our ingredients and get cooking! You won’t want to miss this delicious adventure!
Why I Love This Recipe
- Deliciously Hearty: This casserole is packed with a variety of meats, making it the perfect comfort food for meat lovers.
- Easy to Prepare: With simple steps and minimal prep time, this dish is quick to put together, making it ideal for busy weeknights.
- Cheesy Goodness: The combination of mozzarella and cheddar cheese creates a creamy, gooey texture that everyone will enjoy.
- Versatile Ingredients: You can easily customize this casserole by adding your favorite ingredients or using leftovers!
Ingredients
List of Required Ingredients
- 1 pound ground beef
- 1 pound Italian sausage, casing removed
- 1 cup pepperoni slices
- 1 cup diced ham
- 2 cups cooked pasta (rigatoni or penne)
- 2 cups marinara sauce
- 1 cup mozzarella cheese, shredded
- 1 cup cheddar cheese, shredded
- 1 tablespoon Italian seasoning
- 1 tablespoon garlic powder
- Salt and pepper to taste
- Fresh basil, for garnish
Gather these ingredients before you start. The meat lovers pizza casserole shines when you use quality meats. I love using a mix of ground beef and Italian sausage for rich flavor. Pepperoni and diced ham add a nice touch too.
You'll also need pasta. Rigatoni or penne works best. They hold the sauce and meat well. Marinara sauce is key for that classic pizza taste. Don't forget the cheeses! I use mozzarella for melting and cheddar for extra flavor.
The seasoning is simple yet effective. Italian seasoning and garlic powder enhance the dish. Season with salt and pepper to balance the flavors. Lastly, fresh basil adds a pop of color and freshness when you serve.
This mix of ingredients creates a hearty meal. Each bite is packed with flavor and comfort. You can easily customize it too!

Step-by-Step Instructions
Prepping the Meat Mixture
Start by cooking the ground beef and Italian sausage in a large skillet. Use medium heat and stir often. Cook until the meat is brown and no pink remains. This should take about 8 to 10 minutes. Once cooked, drain any excess fat. This step is key. Too much fat can make your casserole greasy.
Combining Ingredients
Next, add the pepperoni slices and diced ham to your meat mixture. Stir well until the meats are heated through. In a large bowl, combine the cooked pasta, marinara sauce, and Italian seasoning. Mix well to coat the pasta. Then, add the meat mixture to your pasta and sauce. Stir until everything is evenly combined.
Assembling the Casserole
Now it's time to assemble your casserole. Transfer the pasta and meat mixture into a greased 9x13 inch casserole dish. Spread it out evenly. This helps ensure every bite is delicious. Then, sprinkle the shredded mozzarella and cheddar cheese evenly over the top. The cheese will melt and create a nice, gooey layer.
Baking Instructions
Preheat your oven to 350°F (175°C). Once preheated, place your casserole in the oven. Bake for 25 to 30 minutes. Keep an eye on it. You want the cheese to be bubbly and golden brown. Once done, remove it from the oven and let it cool for a few minutes. This allows the flavors to settle. Enjoy your hearty meal!
Tips & Tricks
Perfecting the Flavor
To make your Meat Lovers Pizza Casserole shine, consider adding a few spices. Try adding crushed red pepper for heat. You can also mix in some oregano for added depth. For cheese, mix mozzarella with provolone. This combo gives a rich taste. If you love tanginess, a bit of feta can enhance the flavor.
Cooking Techniques
When browning meat, make sure to cook it over medium heat. This allows it to brown evenly. Stir often to prevent sticking. After cooking, draining the fat is key. Excess fat can make the casserole greasy. Use a colander or spoon to remove it.
Serving Suggestions
This casserole pairs well with fresh salads or garlic bread. A Caesar salad adds a crunchy texture. For garnish, sprinkle fresh basil on top. It gives color and a lovely aroma. You can also add crushed red pepper for a spicy kick.
Pro Tips
- Use Quality Meats: Opt for high-quality ground beef and Italian sausage for a richer flavor and better texture in your casserole.
- Cheese Variations: Feel free to mix up the cheeses! Try adding provolone or gouda for a unique twist on the traditional mozzarella and cheddar.
- Make it Ahead: Prepare the casserole a day in advance and refrigerate it. Just bake it when you're ready to serve for an easy meal.
- Fresh Herbs for Garnish: Don’t skip the fresh basil! It adds a burst of freshness that elevates the overall flavor of the dish.
Variations
Ingredient Swaps
You can easily customize your meat lovers pizza casserole. If you want different meats, try ground turkey or chicken. You can also use cooked bacon for a smoky flavor. For cheese lovers, swap mozzarella with gouda or provolone. If you want a meatless option, replace meat with mushrooms and zucchini. You can use plant-based sausage or even lentils for protein.
Different Pasta Types
Pasta choice can change the dish's feel. While rigatoni or penne works great, you can also use bowtie or fusilli. If you're feeling adventurous, try whole wheat or gluten-free pasta. Each type adds its own twist to the casserole, making it fun to mix things up.
Flavor Enhancements
Adding veggies or spices can bring your casserole to life. Consider bell peppers, onions, or spinach for extra nutrition. You can also add crushed red pepper for some heat. A sprinkle of fresh herbs like parsley or oregano can elevate the flavor. Experiment with your favorite spices to make it your own.
Storage Info
Storing Leftovers
After you enjoy your Meat Lovers Pizza Casserole, store the leftovers right away. Place the casserole in the fridge within two hours of cooking. This helps keep it fresh and safe. Use an airtight container for the best results. Glass or plastic containers work well. If you want to keep it longer, consider freezing.
Reheating Instructions
When you're ready to enjoy leftovers, you have two main options: the microwave or the oven.
- Microwave: Place a portion on a microwave-safe plate. Cover it with a damp paper towel. Heat for about 2-3 minutes. Check if it's hot all the way through. If not, give it more time in short bursts.
- Oven: Preheat your oven to 350°F (175°C). Place the casserole in an oven-safe dish. Cover it with foil to keep it moist. Heat for about 20 minutes or until it's warm.
The oven gives a better texture, while the microwave is quicker.
Freezing Guidelines
To freeze the casserole, let it cool completely first. Cut it into serving sizes for easy thawing later. Wrap each piece tightly in plastic wrap. Then place them in a freezer-safe bag or container. Label the bag with the date. It can last for up to three months in the freezer.
When you're ready to eat frozen portions, move them to the fridge overnight to thaw. You can also reheat the frozen casserole directly from the freezer, but it will take longer.
FAQs
How do I make Meat Lovers Pizza Casserole without pasta?
You can make this dish gluten-free or low-carb by using zucchini or eggplant slices instead of pasta. These veggies give a nice texture and soak up flavors well. You can also use cauliflower rice. Just ensure it is cooked first to avoid sogginess.
Can I make this casserole ahead of time?
Yes, you can. Prepare the casserole up to the point of baking. Cover it well and store it in the fridge for up to 24 hours. When ready to bake, just pop it in the oven. You may need to add a few extra minutes to the bake time.
How do I know when the casserole is fully cooked?
Check for doneness by looking for bubbly cheese and a golden top. You can also insert a food thermometer. The center should reach 165°F (74°C). If it is not hot enough, bake it for a few more minutes.
What can I substitute for marinara sauce?
If you don’t have marinara, you can use pizza sauce or Alfredo sauce. Both add great flavor. You can even try pesto for a twist. Just remember, each sauce will change the dish's taste.
How long will leftovers last in the fridge?
Leftovers will stay fresh for about 3 to 4 days when stored properly. Use an airtight container to keep them safe from air. You can also freeze leftovers for up to 3 months. Just remember to thaw them in the fridge before reheating.
This blog post covered the key ingredients needed for a tasty meat lovers’ pizza casserole, from ground beef to fresh basil. I shared step-by-step instructions on how to prepare, assemble, and bake the dish. Tips for flavor and storage were also included, plus variations for personal preference.
In conclusion, this casserole is easy to make and fun to customize. You can delight in a hearty meal while trying new ingredients or techniques. Enjoy making your casserole and sharing it with friends!